This is an important topic, as they all are. Leading institutional change requires first seeing a problem connected to some kind of action that one can take to make that change. Often, those actions require garnering support from others as well. Not many of us are in a position to make changes all on our own with lasting effects. Instead, people need to connect with others about that change. Collaborating with others requires persuasion and connection of shared understanding of what can be done and how. This also then means people have to agree on the problem, agree and collaborate on the actions, and then be willing to act. A coalitional approach is helpful because then you can impact more of the organization through its people, rather than doing it alone. And, if you are alone working for some kind of change, it is very hard. I would say find an ally to get started.
Change can also take lots of time, energy, and commitment, let alone create problems for you on the job if others are not open to the change that you seek (or if there is reason to move carefully within the organization for a number of reasons). So yes, institutional change is hard but it shouldn't be written off as impossible, just managed and/or leveraged toward alternative solutions.